Walter White, a mild-mannered high school chemistry teacher, discovers he has cancer and resorts to selling drugs in order to provide for his family.

A birthday party for a successful former colleague leaves Walt & Skyler feeling awkward. After Walt refuses to seek an expensive cancer treatment, Skyler stages a Tense family intervention. Meanwhile, Jesse tries to go straight.

As the chemotherapy takes its toll on Walt, his status in the drug world rises. With Jesse’s reluctant help, he sets up a big-time order with Tuco, a dangerous local kingpin. But as Walt grows more fearless, the DEA’s investigation intensifies.

Skyler finds herself in hot water when she attempts to return her sister Marie’s extravagant baby shower gift. Walt and Jesse have even bigger problems, as they scramble to find ingredients for the massive batch of meth they must cook for Tuco.

Walt and Jesse (Aaron Paul) attempt to tie up loose ends. The desperate situation gets more complicated with the flip of a coin. Walt’s wife, Skyler (Anna Gunn), becomes suspicious of Walt’s strange behavior.

As Walt struggles with a life or death decision, he finds himself making a tearful confession to Skyler. Meanwhile, his DEA agent brother-in-law Hank warns Walt Jr. about the dangers of drugs.

The DEA suspects there’s a new drug kingpin operating in Albequerque. Walt & Skyler reveal Walt’s diagnosis to the rest of the family. Jesse makes a surprise visit to his strait-laced family.